What is “Stacking Psilocybin and Lion’s Mane”?
The “Stacking Lion’s Mane and Psilocybin” has been created by the famous mycologist Paul Stamets. It gained global awareness when it was discussed by Stamets and Joe Rogan in the Joe Rogan Experience podcast episode #1035, which aired on the 7th of November 2017. It has since received over 8 million views on YouTube.
In essence, Stamets proposed the idea of combining the consumption of psilocybin (through the form of mushrooms or truffles), Lion’s Mane, and Niacin (vitamin B3).
He hypothesized that this specific ‘Stack” of supplements can have a range of potential positive effects on the brain and our brain health.
These potential effects include primarily the creation of new neurons (neurogenesis), new neural pathways, and even repairing existing neurological damage.
Why is Niacin added to the stack?
Niacin (vitamin B3) is added to the stack purely for increasing the deliverability of the active components in the mushrooms or truffles and Lion’s Mane.
Although Niacin is primarily used to lower cholesterol levels, it also opens up our vasculature. The hypothesis is that niacin’s ability to stimulate the peripheral nervous system could extend the nootropic benefits of the other supplements.
So, the reason Niacin was added to the stack, is that it potentially allows the active components in truffles and Lion’s Mane to be better absorbed throughout the brain and body rather than limiting the absorption to the central nervous system.
What is the Niacin Flush?
The Niacin Flush, or “flushing”, is a skin reddening, itching, and/or burning feeling to start 10 to 20 minutes into the protocol and typically lasts for a maximum of 40 minutes.
However, flushing actually helps to improve blood flow, since the small blood vessels open up more. When Niacin is consumed together with mushrooms or truffles, the potential benefit of the Niacin Flush is that the active components in the mushrooms can be carried to the very tips of our circulatory system and capillaries accessing all parts of the body quickly and efficiently.
What does the Stamets Stacking Protocol look like?
The Stamets Protocol consists of four days on, three days off. This will look as follows:
Day 1: Microdose Truffles + Lion’s Mane + Niacin
Day 2: Microdose Truffles + Lion’s Mane + Niacin
Day 3: Microdose Truffles + Lion’s Mane + Niacin
Day 4: Microdose Truffles + Lion’s Mane + Niacin
Day 5: Lion’s Mane
Day 6: Lion’s Mane
Day 7: Lion’s Mane
Note: As can be seen in the table above, Lion’s Mane can also be consumed on the off-days.
Repeat this cycle for a maximum of one month. It is advised to take at least a two to four-week break after completing a one-month cycle.
How much do I need to consume?
According to the Stamets Protocol, Based on a person of 70 kilograms, the following dosages are advised:
Psilocybin Truffles: 0.5 – 1 gram
Lion’s Mane Erinacines/Hericinones: 50 – 200 mg
Niacin: 100 – 200 mg
Based on this, we recommended the following dosages of our products:
Psilocybin Truffles: 0.5 – 1 gram (0.5 – 1 dose)
Lion’s Mane: 3 v-caps which contain both hot water extract (Hericinones) and alcohol extract (Erinacines)
Niacin: 1-2 tablets (build-up, see below)
The Niacin dose needs to be relatively high in order to achieve the flush. Since you build up a tolerance for Niacin, in general, the Niacin Flush gets less strong after a few days of consumption. As the Niacin Flush is desired in this protocol for maximum deliverability, we recommended building up the Niacin intake during the dosing days, and to take a break on the off days.
So, the complete protocol can look like this:
Day 1: Microdose Truffles (0.5-1 gram) + Lion’s Mane (3 v-caps) + Niacin (100 mg = 1 tablet)
Day 2: Microdose Truffles (0.5-1 gram) + Lion’s Mane (3 v-caps) + Niacin (100 mg = 1 tablet)
Day 3: Microdose Truffles (0.5-1 gram) + Lion’s Mane (3 v-caps) + Niacin (150 mg = 1.5 tablets)
Day 4: Microdose Truffles (0.5-1 gram) + Lion’s Mane (3 v-caps) + Niacin (200 mg = 2 tablets)
Day 5: Lion’s Mane (3 v-caps)
Day 6: Lion’s Mane (3 v-caps)
Day 7: Lion’s Mane (3 v-caps)
Note that personal preference can vary and that you can tweak and experiment to find your own personal sweet spot.
However, it is advised to take the above recommendations into consideration, as they aim at the so-called “minimum effective dose”. This means that these amounts should be consumed in order for the protocol to have the desired effects, and yet will not make you feel too uncomfortable.
This last part is important, as in general microdosing the aim is to feel comfortable and relaxed, with this protocol this is not the goal. This protocol strictly aims to achieve its proposed benefits of improved brain health and cognitive functioning.
When should the supplements be consumed?
The products should be consumed in the morning, as psilocybin can have an effect for 6 hours or more. Therefore, in order to prevent trouble with sleeping, it is highly recommended to consume the products in the morning before breakfast, in the following order:
Before breakfast: Consume the truffles and Lion’s Mane.
After breakfast / ideally 15 minutes later: Consume the Niacin.
It is advised to consume the Niacin around 15 minutes later and after eating for two reasons:
- The Niacin Flush will coincide with the truffles and Lion’s Mane.
- The Niacin Flush will cause more discomfort on an empty stomach, so it’s best to consume after eating a meal.
Can’t I just take No-Flush Niacin?
No. The reason for this is that Niacin is added to the stack for deliverability, for which the Niacin Flush is required.
“No-Flush” Niacin products are actually another substance, namely inositol hexanicotinate. So you will not experience the Niacin Flush, but also not benefit from the proposed benefits the Flush offers.
*We are not affiliated with Paul Stamets in any way.
**This information is for informational purposes only and has not been reviewed or approved by EFSA. Microdose Pro supplements are not medicines and should never be used as a substitute for regular medication.
I took these microdoses for the first time 2 months ago to go to a museum with friends, and I would never have paid so much attention to the small details of a painting.
concentration is brutal.
I am a painter, and some times are not very creative.
but of course with microdosing, it’s non-stop.
It reduces my appetite, which also means that it lowers my anxiety state.
and with 4 doses I can’t say much more but I’m very very happy
Im happy that I found you and you are taking part of my improving myself. Truffels work great, more than I was expecting 🙂 They will stay with me for sure !
It is being a pleasant and curious journey of discovery. The effects can be – and so they are – just positive – Why do not trying it?
the stamet protocole was for me so beneficial in every way , I experienced an increase of focus , productivity , boost of confidence , healings , less thinking more actions , more tune to my emotions and feelings and intuitions , more présent , more creativity , I recommend it 100 percent .
A whole new world.. I’ll continue into this rabbit hole!!
Microdosing has helped me with my mood by keeping my mind in the moment. I will definitely continue.
I like how I’m in tune with myself.
could nor be more happy ! great service and costumer support
This came at exactly the right time for me. I was diagnosed with ADD and needed medicine for it, but i didn’t want to take the methylphenidate because it’s so bad for you. After some research i saw this and thought this is natural why not give it a try. Well this blew my mind. My mood changed, i can keep up with my household, i quit smoking within a month after trying to quit for years! I’m so thankful i found this and the coaching session was very nice, I learned a lot. Also i was standing still in life and this helped me get things in perspective and now my ambition is sparked again! Looking forward to the future and will never stop taking truffels for my mental health! Thank you so much for starting this company and the follow ups that you all do!
Its like cleaning out my mental closet…. never re-arranged so much stuff in years… my creativity got a boost…. thinking is more clear and mental awareness is very conscious in all my moves and gestures so far… in my sports I feel like being more focused…. tomorrow I will start my second week….
I’m extremely pleased with my first month of microdosing. I feel better than in a long time. There’s a significant change in my mood and I notice an overall feeling of lightness and freshness even on the days I’m not microdosing. The only thing I’m regretting is not having tried this out sooner.
Already got several friends that have adhd, or Dementia, or other problems to order from you. And more are on the way to order from you
I’m glad I encountered with microdosing. I think you have a nice product and you have a good support. Just to be able to order and get it relatively fast is nice.
You are more in the moment or something, you know?
Great experience until now. I work as a spiritual adviser and healer, and I can already see the benefits in terms of mental expansion and flexibility, clarity, creativity, and grounding. On the days I take truffles, I definitely feel more grounded, connected to my body and mind, and much sharper. I also can notice a direct impact on my surroundings, where people seem to adjust to my elevated mood, focus, and overall vibration. As I work from home, along with my wife and baby boy, I can feel on these days a more joyful and grounded connection with them, which is clearly a reflection of how I feel inside… And I can see these feelings start to ripple on the days without truffles.
I am not sure how to describe this in words, but I try to get friends to also try it. People around me tell me that I am kinder, more present and less panicky. I know it works, I can feel it, but it is something deep and intangible.
Def doing this again
I find they definitely help my mood and focus my mind on my feelings
i am so happy that i found your company. i am treating my addiction with it and since my 6 dose it is working so good. also i am much more motivated than usual, much more productive and my mood is so much better. overall i really feel like a better version of me allready.
Unfortunately I was not able to finish my strip due to personal circumstances. However, I must say that the 2 weeks that I did use it were great. I noticed an increasing awareness of my feelings and emotions, followed by a tackling of the problems that came forward. Will continue to explore microdosing.
On the first dose I felt like a real boost a few hours after I ate it, and the day after my mood was slightly better. Then every three days it was like charging up my creativity (I composed more than 3 songs with my guitar in one week) and my focus at work was constant. My experience with psilocybin is a real success.
Happy to recieve the support and emails ..Personal issues prevented me from finishing the strip..so will try again..hopefully they will still be potent and viable
It definitely helped with my articulation that impacts my productivity and somewhat calmness. I’m a guy all over the place.
I love it. I feel like I can accomplish a lot even on days where I sleep bad!
For the record, sleeping bad have nothing to do the with truffles
Hey! Well. I finished my first strip 1 week ago. I bought the starter pack, so I got two and I decided to continue on with the second strip right after.
I will be taking at least a week off when I am done with this in 2 weeks ^^Its quite neat already and I do feel a boost in my mood, but I feel a big difference when I talk to people, it feels amazing! Also, its easier for me to switch from task to task and stay focused for a longer time, which is good when you have adhd :p Happy thoughts!
I find the Microdose Beginners Protocol to be an enriching experience, journaling and reflecting on daily intentions while microdosing has been a very positive experience for me.
It is an exciting offering, and I’m surprised by its effect on my mind. I think it’s too early to tell what will be the overall outcome of microdosing on my mind but I ordered two more strips and for now, I’m happy to continue this experiment. I’m grateful that, a company like yours exists and I applaud your efforts to bring microdosing to a wide public.
finally found a microdosing system that works. it was a true all round much needed boost. after a couple of months its time for a short break, excited about firing shit up again. great customer support too. dank u wel !
Microdosing helped me clearing the fog I was carrying around after my depression. After the first dose I experienced a renewed connection with the earth again, felt like I landed. After all doses I can say I am more relaxt, more productive and more creative overall. Thanks for this experience! Will have a regular checkup now and then.
The customer follow-up service is great. It doesn’t feel like there hounding you and I actually feel like they want to help. These are little packages of wounded and have sparked my interest to research more into the effects of psilocybin and other fungi.
There is a lot to be said with these and even my wife noticed a difference in me. I use these to be a better person and to appreciate life that’s the deep answer I can give you. On the other hand I can chop up and mix jungle drum and bass all night and not get bored. These are great for creativity and for positivity.
I really liked the experience and the service!
Still learning how 2 use it in the best way
I can go for hours and my brain can multitask on a dosing day. Microdosing also helps me think more laterally – I come up with new solutions to challenges, or suddenly think of a fresh way of doing something I’ve been doing the same forever. My OCD thought patterns are diminished and I am able to focus a lot more on my work. I tend to enjoy usually “boring” work much more.
Microdosing has had a significant and positive impact on my mental health and wellbeing and I can recommend it to anyone! Thanks, Microdose Pro for offering not only a high-quality product but also a supportive experience. Much love <3
This has been a game changer for my mental health in general. Only downside, the doses were very different in size so I highly recommend that you buy a microgram scale to make sure you have a reasonable amount as I was quite effected two of the days due to a too large dose.
It works. For personal reasons i didn’t followed program, i did 1 day microdose and 4 or 5 days off, but my mood improved drastically, productivity as well and it helped me to deal with such mental hit as best friends death… TOTALLY RECOMMEND IT!
Microdosing helped open doors to my inner creativity that have been shut for a long time. I can feel positive ideas and projects bubble up in my mind!
It has strengthened the body awareness as well.
Very glad with first results and ready for advanced protocol.
I feel me more relax, my concentration is better,
The product is great, unfortunately, 2 of the microdose got mold buy you customer support team handle very good the issue, I would definitely get another package
Very good product, very good service.
Great feeling, I take about 0,5g of the trufles in beginners protocol with the lion mane 2X2.
Very light buzz, feel happy and more sociabele overall.
Thank you for this excellent service and product.
I generally had a positive experience but I would not advertise it for “improving focus”. I did feel the easy from worries and non-clinical anxiety, I could only guess that it worked like antidepressants (I never took any so I can’t judge). It helped me to let go of tensions. However, even though I took 1/4 of the dose, it was not natural for me to concentrate, I felt a bit disorientated. I also didn’t like the effect whilst doing my regular yoga / meditation. Better without.
The verdict is that I can reccomend it on the free day, when you need to unwind and don’t have important things lined up.
I can say it’s been a game-changer for me. After following the protocol for a while I started having an easier approach to life. I was more excited and proactive: when I had to start a new project, I didn’t feel that initial “anxiety” of getting into a new activity. On top of that my chronic pain improved too. Definitely helped.
It helped me to overcome my depression. Using these truffles was pretty amazing. I felt stronger and energy levels went up. It was like having fresh air in my head. Thank you.
I wanted to wait a while till I had used it for a couple of weeks before sharing my thoughts.
The first day I took a half portion and did not feel so much. The second day I decided to go all the way and took my first full portions. This is how my day looked like:
I made some thea from it and the taste wasn’t that bad. After 45 min it kicked in and I felt really positive and energized. It gave me extra motivation to sport and it felt really good to sport in combination with music. It felt a little bit like a small discoparty. Afterwards I took a cold shower and was extra motivated to work on stuff I normally postpone. I did all my administration and got lots of work done. I have been taking it for a few weeks 3 times a week. I generally notice that
it gives me more focus, more energy and just sort of clears my mind for new ideas.
Thank you for the experience! And keep up the good work!
I loved the handwritten text that was found in the package. It personalized the purchase with micropro. I felt more focused on the days that I was microdosing and felt like I enjoyed more what I was doing on that day. I was definitely more present.
On the days that i took the microdose, i didn’t feel like doing anything, just enjoy being. I felt like having ALL THE TIME IN THE WORLD. The days in between, my mood was great and I was productive. Also lot’s on insights, thankful.
The Mircodose helped me focus much more!!! It came as a blessing. I finished one month and will keep on trying it for one more ?
Nicely packed and dosed. Fast and discrete shipping.
It helped me for my mood, energy, sleep and creativity! Def doing this again
Love Microdose Pro, really helpful for my mood, creativity, productivity and focus. It’s a real gamechanger!
Was skeptical in the beginnig but I have to say that the positive effects are outstanding.
I’ve been doing it for a while now. I would say I can feel constant improvement in the mood.
The government should distribute this for free for public health!
Good product. It Really helps with the mood and creativity. Loved the packaging
This was my first experience with micro dosing. It was really successful for my creativity!
Interesting effects while concepting and brainstorming
Awsome choice for everyone that wants some boost in his daily productivity and creativity
A nice boost for energy and productivity. I Totally recommend it.
Have been using it since few days now. You can definetly feel something different in your body.
My mood was positively affected.
When in use, Microdose increases my tunnel vision. This product will influence everyone differently… As a person I’m full of ideas, outgoing and bubbly however lack of concentration when needed; Whereas Microdose does that little extra for me, when I have to be productive and sit place on work mode. Regarding emotion, I feel good but I already felt good when taking it, so didn’t feel much of a difference. Overall it did the trick where I needed it, and that was staying in focus. Productivity went like a rocket.
As you can see it didn’t work on me in a way that I was more creative or productive. It made me have a better connection with myself and others around me. So it helps me in my own development.
Loved it! Thanks for introducing me Kai!
Amazing experience, felt more in tune with my emotions the whole day. It shuts up the “I gotta, gotta, gotta” voice for me! ?